1 Medical Microbiology and Immunology Department, Military Medical Academy, Cairo, Egypt.
2 Microbiology and Immunology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
3 Medical Microbiology and Immunology Department, Faculty of Science, Ain-Shams University, Cairo, Egypt.
Research Article
GSC Advanced Research and Reviews, 2022, 12(01), 091–100.
Article DOI: 10.30574/gscarr.2022.12.1.0187
Received on 10 June 2022; revised on 16 July 2022; accepted on 18 July 2022
The purpose of this study is to assess the impact of low-frequency electromagnetic fields (LF-EMFs = 0.5 MHz) on the phenotypic and genotypic levels concerning the antibiotic resistance, antimicrobial-resistant (AMR) genes, and resistance mechanisms of Pseudomonas aeruginosa (P. aeruginosa). In this study, the bacterial isolates were exposed to 0.5 MHz and then inoculated to a new medium for the assessment of their antibiotic sensitivity. The results showed that there were statistically significant changes in the antibiotic sensitivity upon exposure to extremely low-frequency waves along with significant changes in the antimicrobial genes and resistance mechanisms. We conclude that extremely LF-EMFs appeared to be effective in changing the antibiotic sensitivity and could be considered a future promising method for controlling bacterial resistance.
Electromagnetic Fields; Antibacterial Effects; Resistance; Pseudomonas; NGS
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Ahmed Hamdy Badr, Mohamed Sherif, Ahmed Abdelaziz Sayed and Mostafa Mohamed Elnakib. Effects of extremely low-frequency electromagnetic fields on the susceptibility and resistance mechanisms of multi-drug resistant Pseudomonas aeruginosa. GSC Advanced Research and Reviews, 2022, 12(1), 091-100. Article DOI: https://doi.org/10.30574/gscarr.2022.12.1.0187