1 Faculty of Health Sciences, Department of Basic, Biomedical and Pharmaceutical Sciences, Adam Barka University of Abéché, Chad; P.O. Box: 1173
2 Department of Medicine, Faculty of Health Sciences and Technology, Chair of Basic Sciences, Gamal Abdel Nasser University of Conakry, P.O. Box 1147, Republic of Guinea.
3 Biomedical Laboratory of the China-Guinea Friendship Hospital, Kipé, Cité des Médecins, Ratoma 30 Commune, P.O. Box 710, Conakry, Republic of Guinea.
4 Department of Biology, Faculty of Sciences, Gamal Abdel Nasser University of Conakry, P.O. Box: 1147, Republic of Guinea
5 Department of Microbiology, Institute of Applied Biology Research of Guinea (IRBAG/Kindia; P.O. Box: 146) Gamal Abdel Nasser University of Conakry, P.O. Box: 1147, Republic of Guinea
6 Faculty of Human Health Sciences, Department of Biomedical and Pharmaceutical Sciences, University of Ndjamena, Ndjamena, Chad; BP: 1117
Received on 30 November 2025; revised on 07 January 2026; accepted on 09 January 2026
Introduction: Hepatitis B is a serious viral infection of the liver caused by the hepatitis B virus (HBV). This infection leads to inflammation of the liver, which can become chronic and result in liver cirrhosis and hepatocellular carcinoma.
Objective: To determine the seroprevalence of HBsAg in patients at the Abéché University Hospital in Chad.
Material and Methods: This was a prospective cross-sectional study conducted from April 1, 2022, to December 31, 2022, on a total of 845 patients aged 15 to 60 years seen in consultation at the Abéché University Hospital. HBsAg detection was performed using chromatography, and confirmation was carried out using the immunoassay method (ELISA).
Results: The analysis showed that among the 845 patients tested, 112 were positive for HBsAg, representing an overall prevalence of 13.3% (112/845). Males represented 50.9% (430/845), while females represented 49.1% (415/845); the sex ratio was 1.03. The most affected age groups were 26–35 years (34.82% = 39/112), followed by 15–25 years (25.89% = 29/112). By occupation, farmers/livestock breeders were the most represented (61/112 = 54.46%), followed by homemakers (20.53% = 23/112). By marital status, married individuals were more affected (58.93% = 66/112) than single individuals (41.07% = 46/112).
Conclusion: The seroprevalence of hepatitis B virus was relatively high in the population of Abéché, with more pronounced predominance among young people, married individuals, and particularly those working in agriculture and livestock farming. Combating the spread of this endemic infection in Chad requires strengthened strategies, including vaccination, targeted screening, and public awareness campaigns.
Seroprevalence; HBsAg; Associated factors; Abéché University Hospital; Chad
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Hissein Issaka Nourdja, Abdoulaye Makanéra, Taliby Dos Camara, Aissatou Boiro, Mamadou Boundoukhoura Bah, Thierno Amadou Labé Balde, Ibrahima Sory Sow, Adawaye Chatte, Mamadou Ciré Diallo and Mamadou Yéro Boiro. Evaluation of HBsAg seroprevalence in patients seen in consultation at the University Hospital of Abéché-Chad. GSC Advanced Research and Reviews, 2026, 26(1), 122-128. Article DOI: https://doi.org/10.30574/gscarr.2026.26.1.0012