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Phytochemical investigation of the bark extract of Carissa sessiliflora Brongn. Ex Pichon Syn. Carissa bispinosa (L) Desf.ex Brenan (Apocynaceae), endemic to Madagascar

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  • Phytochemical Investigation of The Bark Extract of Carissa Sessiliflora Brongn. Ex Pichon Syn. Carissa Bispinosa (L) Desf.ex Brenan (Apocynaceae), Endemic To Madagascar
  • Phytochemical investigation of the bark extract of Carissa sessiliflora Brongn. Ex Pichon Syn. Carissa bispinosa (L) Desf.ex Brenan (Apocynaceae), endemic to Madagascar

Andrianarijaona Mamy 1, 2, Ralaivaon-dratsitonta Jumaël Edith Fabrice 1, 3, *, Tiandreny Hazara Jipaty 1, Fiatoa Barthelemy 1, 3, Robijaona Rahelivololona Baholy 4 and Fatiany Pierre Ruphin 1, 2

1 Doctoral School of Geosciences, Physics, Environmental Chemistry and High-Pathogen Systems (GPCEHP), University of Toliara, Toliara 601-Madagascar.
2 Field of Science and Technology BP. 187, University of Toliara, Toliara 601 Madagascar.
3 Androy Regional University Center (CURA), University of Toliara, Madagascar.
4 Polytechnic High School of Antananarivo, University of Antananarivo, Antananarivo, Madagascar.
 
 
Research Article
GSC Advanced Research and Reviews, 2025, 24(02), 205-212.
Article DOI: 10.30574/gscarr.2025.24.2.0246
DOI url: https://doi.org/10.30574/gscarr.2025.24.2.0246
Received on 08 July 2025; revised on 15 August; accepted on 18 August 2025
 
Carissa sessiliflora Brongn. ex Pichon Syn. Carissa bispinosa (L) Desf.ex Brenan (Apocynaceae) is endemic to western Madagascar. Due to its therapeutic properties, this plant plays an important role in traditional medicine and is used to treat infections and malaria.
Phytochemical investigations of the cyclohexane extract of this plant's stem bark have led to the isolation of four pure compounds. The chemical structures of these compounds were elucidated using spectroscopic analysis techniques (1D and 2D NMR) and mass spectrometry (ESI-MS in positive mode), as well as by comparing the data with that in the literature.
These products are attributed to the chemical family of pentacyclic triterpene compounds.
 
Carissa sessiliflora Brongn ex. Pichon; Apocynaceae; Pentacyclic triterpene; NMR (1D, 2D) and EI.MS
 
https://gscarr.gsconlinepress.com/sites/default/files/fulltext_pdf/GSCARR-2025-…

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Andrianarijaona Mamy, Ralaivaon-dratsitonta Jumaël Edith Fabrice, Tiandreny Hazara Jipaty, Fiatoa Barthelemy, Robijaona Rahelivololona Baholy and Fatiany Pierre Ruphin. Phytochemical investigation of the bark extract of Carissa sessiliflora Brongn. Ex Pichon Syn. Carissa bispinosa (L) Desf.ex Brenan (Apocynaceae), endemic to Madagascar. GSC Advanced Research and Reviews, 2025, 24(2), 205-212. Article DOI: https://doi.org/10.30574/gscarr.2025.24.2.0246

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