Posterior reversible encephalopathy syndrome with functional and motor sequelae: A case report

Posterior Reversible Encephalopathy Syndrome (PRES) is a rare clinicoradiological neurological disorder, initially elucidated in 1996, Since this first description of PRES numerous case reports and case series, as well as retrospective observational studies describing the syndrome have been published. Importantly, no randomized controlled studies have been performed, We present the case of a young patient with no significant medical history who presented with neurological symptoms consistent with Posterior Reversible Encephalopathy Syndrome (PRES). Brain MRI confirmed the diagnosis of Posterior Reversible Encephalopathy Syndrome (PRES). Additionally, the etiological assessment yielded negative results. A notable aspect in our patient's case is the persistence of sequelae, characterized by dexterity and grip impairment on the right side, hindering various activities of daily living. The diagnosis of PRES is both radiological and clinical, with MRI playing a crucial role. Treatment is primarily symptomatic, sometimes requiring intensive care unit admission. Prognosis is favorable in the majority of cases, but severe complications and even death can occur. The reversibility of initial symptoms is well-documented in the literature. Long-term functional impairment outcomes following PRES have not been adequately characterized in the literature. Therefore, it is necessary to conduct follow-up screenings in more patients presenting both typical and atypical PRES syndromes. This will provide insight into whether the functional and motor sequelae of PRES are less reversible.