Comparative analysis of the hematological Profile and alloantibodies of pregnant women in a tertiary institution – North-Central Nigeria

The third world countries have suffered challenges relating to public health, ranging from high cost of healthcare, poverty and lack of diagnostic equipment and accessories. One of the salient issues is universal antenatal antibody screening. This study aimed to appraise the alloantibodies in comparison with hematological profiles of pregnant women accessing ante-natal care at a tertiary Institution – in Jos, North-Central, Nigeria. A total of 200 consenting pregnant women receiving ante-natal care in the Jos University Teaching Hospital, Jos, Nigeria, were recruited into this study for a period of one month. Each participant was interviewed with a pretested, structured, interviewer‑administered questionnaire. Blood sample was collected from each participant with minimal stasis from the antecubital vein via sterile syringe and needle into (EDTA) bottles. Full blood count and antibody screening were done by standard methods. Results showed that there was a decrease in the RBC, PCV, Hb, MCH, MCHC, RDW, WBC, and LymP WBC and increase in MCV, NeuP, MonP, EosP, and BasP values of participants with alloantibodies compared to those without, also with no significant (p > 0.05) between the groups. There was no difference in the platelet counts of both groups. Alloantibodies have effect on the hematological profiles (RBC, PCV, Hb, MCH, MCHC, RDW, WBC, and LymP WBC, MCV, NeuP, MonP, EosP, and BasP) of pregnant women accessing ante-natal care at in JUTH, Nigeria.