1 Department of Food Biotechnology, Kazan National Research Technological University, Kazan, Russia.
2 Department of Biotechnology, Institute of Pharmacy named by A.P. Nelyubin, FSAEI НЕ I.M. Sechenov First MSMU of МОН of Russia (Sechenovskiy University), Moscow, Russia.
3 Department of Biochemistry, Biotechnology and Pharmacology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
4 Department of Food Biotechnology, Kazan National Research Technological University, Kazan, Russia.
Research Article
GSC Advanced Research and Reviews, 2025, 23(03), 138-144.
Article DOI: 10.30574/gscarr.2025.23.3.0168
Received on 09 May 2025; revised on 14 June 2025; accepted on 17 June 2025
The physicochemical properties of the lectin of the lower fungus, micromycetes Alternaria alternate 4 have been studied. It was found that the lectin of the micromycetes Alternaria alternate 4 is stable over a wide range of temperatures and pH values (5-70oC and pH 6.0-9.0). The greatest activity of lectin was observed at a temperature of 5-50 °C and a pH of 6.5-8.5. The increased activity of Alternaria alternate 4 lectin was facilitated by the presence of divalent Ca2+, Mn2+, and Zn2+ ions in the reaction mixture, which indicates that Alternaria alternate 4 lectin is a metal-dependent glycoprotein. Alternaria alternate 4 lectin had the ability to bind simple carbohydrates. The activity of Alternaria alternate 4 lectin was inhibited to a greater extent by galactose, which indicates that Alternaria alternate 4 lectin belongs to the group of galactose-binding lectins.
Lectins; Micromycetes; Alternaria alternate; Physicochemical properties
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Zinurov M.R, Zinurova E.E, Bagaeva T.V and Sysoeva M. A. Physicochemical properties of micromycetes Alternaria alternate 4 lectin. GSC Advanced Research and Reviews, 2025, 23(3), 138-144. Article DOI: https://doi.org/10.30574/gscarr.2025.23.3.0168